“Animal models are essential for several biomedical research fields such as cancer biology and therapeutics, neuroscience, pharmacology and toxicology, neurobiology of diseases, endocrinology, public health, palliative medicine, also, in studies in human and animal biology and for the discovery and testing of new drugs, vaccines, and other biologicals [...] Currently, these models address current research priorities, considered as those imposing major global threats to human and animal health.”
– Adriana Domínguez-Olivia, et al., 20231
The National Institutes of Health (NIH), through the Department of Health and Human Services (DHHS), is supporting biomedical research projects to improve the rigor, reproducibility, and translatability of animal models via the development and implementation of broadly applicable technologies, tools, and resources. This opportunity stresses that the proposed studies, resources, models, or technologies must either explore multiple organ systems or be applicable to diseases and processes impacting many organ systems and must address research interests of multiple NIH Institutes & Centers (IC’s).